Downregulation of CDKN2A and Suppression of Cyclin D1 Gene Expressions in Malignant Gliomas
نویسندگان
چکیده
منابع مشابه
Downregulation of CDKN2A and suppression of cyclin D1 gene expressions in malignant gliomas
BACKGROUND Malignant gliomas are the most common in central nervous system cancer. Genome-wide association study identifies that CDKN2A was a susceptibility loci for glioma. The CDKN2A/cyclin-dependent kinase 4, 6/Retinoblastoma protein (Rb) pathway is thought to play a crucial role in malignant gliomas pathogenesis. We have investigated the expression of CDKN2A for potential correlations with ...
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ژورنال
عنوان ژورنال: Journal of Experimental & Clinical Cancer Research
سال: 2011
ISSN: 1756-9966
DOI: 10.1186/1756-9966-30-76